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In chronic treatment, a significant decrease observed in the dorsal raphe is along with increases in the substantia nigra, the lateral caudate, and the accumbens nucleus

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As your immune system activates: White blood cells increase activity Mild inflammation occurs at the injection site You may feel tired or slightly unwell Common side effects listed by the NHS include: Soreness, redness or swelling at the injection site Mild fever Fatigue Headache Muscle aches These symptoms typically settle within 24–72 hours and indicate that your immune system is responding appropriately